As of 2025, the population of Sao Tome and Principe is approximately 0.24 million people (240 254), making it the 181st most populous country in the dataset of 217 countries, with a 0.00% share of the combined total.
Over the past five years the population of Sao Tome and Principe changed by +10.49%, and over the past ten years by +19.95%. By five-year growth, Sao Tome and Principe ranks 48th of 217 countries; in terms of momentum, growth is accelerating — from +1.66% to +2.02% per year.
| Year | Population | Diff | Diff % | Share of Universe |
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